Glial reprogramming papers
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Regulating the formation of Müller glia-derived progenitor cells in the retina
Olivia Taylor, Heithem El-Hodiri, Isabella Palazzo, Levi Todd, Andy Fischer - 2024.- Glia
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A multiplexed, single-cell sequencing screen identifies compounds that increase neurogenic reprogramming of murine Muller glia
Amy Tresenrider, Marcus Hooper, Levi Todd, Faith Kierney, Nicolai Blasdel, Cole Trapnell, Thomas A. Reh - 2023 - eLife
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Controlling donor and newborn neuron migration and maturation in the eye through microenvironment engineering
Jonathan R. SoIucy, Levi Todd, Emil Kriukova, Monichan Phaya, Volha V. Malechkaa, John Dayron Riveraa, Thomas A. Reh and Petr Baranov 2023 - PNAS
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Reprogramming Müller glia to regenerate ganglion-like cells in adult mouse retina with developmental transcription factors
Levi Todd, Wesley Jenkins, Connor Finkbeiner, Marcus J. Hooper, Phoebe Donaldson, Marina Pavlou, Juliette Wohlschlegel, Norianne Ingram, Fred Rieke & Thomas Reh - 2022 Science Advances
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Efficient stimulation of retinal regeneration from Müller glia in adult mice using combinations of proneural bHLH transcription factors
Levi Todd, Marcus Hooper, Alex Haugan, Connor Finkbeiner, Nikolas Jorstad, Nicholas Radulovich, Claire Wong, Phoebe Donaldson, Wesley Jenkins, Qiang Chen, Fred Rieke, Thomas Reh - 2021 Cell Reports
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Comparative Biology of Vertebrate Retinal Regeneration: Restoration of Vision through Cellular Reprogramming
Levi Todd & Thomas Reh - 2021 Cold Spring Harbor Perspectives In Biology
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STAT signaling modifies Ascl1 chromatin binding and limits neural regeneration from muller glia in adult mouse retina
Nikolas Jorstad*, Matthew Wilken*, Levi Todd*, Connor Finkbeiner, Paul Nakamura, Nicholas Radulovich, Marcus Hooper, Alex Chitsazan, Brent Wilkerson, Fred Rieke & Thomas A Reh - 2020 Cell Reports
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Gene regulatory networks controlling vertebrate retinal regeneration
Thanh Hoang, Jie Wang, Patrick Boyd, Fang Wang, Clayton Santiago, Lizhi Jiang, Sooyeon Yoo, Manuela Lahne, Levi Todd, Meng Jia, Cristian Saez, Casey Keuthan, Isabella Palazzo, Natalie Squires, Warren A Campbell, Fatemeh Rajaii, Trisha Parayil, Vickie Trinh, Dong Won Kim, Guohua Wang, Leah J Campbell, John Ash, Andy J Fischer, David R Hyde, Jiang Qian, Seth Blackshaw - 2020 Science
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Matrix-metalloproteinase expression and gelatinase activity in the avian retina and their influence on Müller glia proliferation
Warren A Campbell IV, Ameya Deshmukh, Sydney Blum, Levi Todd, Ninoshka Mendonca, Jessica Weist, Joshua Zent, Thanh V Hoang, Seth Blackshaw, Jennifer Leight, Andy J Fischer - 2019 Experimental Neurology
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Retinoic acid-signaling regulates the proliferative and neurogenic capacity of Müller glia-derived progenitor cells in the avian retina
Levi Todd, Lilianna Suarez, Colin Quinn, Andy J Fischer - 2018 Stem Cells
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BMP and TGFβ signaling regulate the formation of Müller glia derived progenitor cells in the avian retina
Levi Todd, Isabella Palazzo, Natalie Squires, Ninoshka Mendonca, Andy Fischer - 2017 Glia
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Jak/Stat signaling regulates the proliferation and neurogenic potential of Müller glia-derived progenitor cells in the avian retina
Levi Todd, Natalie Squires, Lilianna Suarez, Andy Fischer - 2016 Scientific Reports
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Wnt/β-catenin-signaling and the formation of Müller glia derived progenitors in the chick retina
Donika Gallina, Isabella Palazzo, Lillia Steffenson, Levi Todd, Andy J Fischer - 2016 Developmental Neurobiology
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mTor signaling is required for the formation of proliferating Müller glia-derived progenitor cells in the chick retina
Christopher P Zelinka, Leo Volkov, Zachary A Goodman, Levi Todd, Isabella Palazzo, William A Bishop, Andy J Fischer - 2016 Development
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Selected for cover! -
Heparin-binding EGF-like growth factor (HB-EGF) stimulates the proliferation of Müller glia-derived progenitor cells in avian and murine retinas
Levi Todd, Leo Volkov, Chris Zelinka, Natalie Squires, Andy Fischer - 2015 Molecular and Cellular Neuroscience
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Hedgehog signaling stimulates the formation of proliferating Müller glia-derived progenitor cells in the chick retina
Levi Todd & Andy Fischer - 2015 Development
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A comparative analysis of Müller glia-mediated regeneration in the vertebrate retina
Donika Gallina, Levi Todd, Andy J Fischer - 2014 Experimental Eye Research
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Neuro-immune papers
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Monocyte invasion into the retina restricts the regeneration of neurons from Müller glia
Nicolai Blasdel, Sucheta Bhattacharya, Phoebe Donaldson, Thomas Reh & Levi Todd - 2024 - Journal of Neuroscience
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NFkB signaling promotes glial reactivity and suppresses Müller glia mediated neuron regeneration in the mammalian retina
Isabella Palazzo, Levi Todd, Thanh V Hoang, Thomas A Reh, Seth Blackshaw, Andy J Fischer - 2022 Glia
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Microglial depletion abolishes ischemic preconditioning in white matter
Margaret A Hamner, Ashley McDonough, Davin C Gong, Levi Todd, German Rojas, Sibylle Hodecker, Christopher B Ransom, Thomas A Reh, Bruce R Ransom, Jonathan R Weinstein - 2022 Glia
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Microglia suppress Ascl1-induced retinal regeneration in mice
Levi Todd, Connor Finkbeiner, Claire Wong, Marcus Hooper & Thomas Reh - 2020 Cell Reports
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Reactive microglia and IL1β/IL-1R1-signaling mediate neuroprotection in excitotoxin-damaged mouse retina
Levi Todd*, Isabella Palazzo*, Lilianna Suarez, Xiaoyu Liu, Leo Volkov, Thanh Hoang, Warren Campbell, Seth Blackshaw, Ning Quan &, Andy Fischer - 2019 Journal of Neuroinflammation
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Reactive microglia and macrophage facilitate the formation of Müller glia derived retinal progenitors
Andy J Fischer, Christopher Zelinka, Donika Gallina, Melissa A Scott, Levi Todd - 2014 Glia
Other papers
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Inducing Neural Regeneration from Glia Using Proneural bHLH Transcription Factors
Levi Todd - 2023 Advances in Experimental Medicine and Biology
Conference paper -
Valproic Acid for a Treatment of Retinitis Pigmentosa: Reasons for Optimism and Caution
Levi Todd and Christopher Zelinka - 2017 Journal of Neuroscience
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Systemic gene delivery transduces the enteric nervous system of guinea pigs and cynomolgus macaques
Sara E Gombash, Christopher J Cowley, Julie A Fitzgerald, Christina A Lepak, Mitchell G Neides, Kathryn Hook, Levi Todd, Guo-Du Wang, Christian Mueller, Brian K Kaspar, Eric C Bielefeld, Andrew J Fischer, Jackie D Wood, Kevin D Foust - 2017 Gene Therapy
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Comparative analysis of glucagonergic cells, glia, and the circumferential marginal zone in the reptilian retina
Levi Todd, Lilianna Suarez, Natalie Squires, Christopher Paul Zelinka, Kevin Gribbins, Andy J Fischer - 2016 Journal of Comparative Neurology